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RiVax®

Paper

Effect of single-point mutations on the stability and immunogenicity of a recombinant ricin A chain subunit vaccine antigen

Thomas, J.C., et al., Effect of single-point mutations on the stability and immunogenicity of a recombinant ricin A chain subunit vaccine antigen. Hum Vaccin Immunother, 2013. 9(4).
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Pilot Phase IB Clinical Trial of an Alhydrogel-Adsorbed Recombinant Ricin Vaccine

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Vitetta, E.S., J.E. Smallshaw, and J. Schindler, A Small Phase IB Clinical Trial of an Alhydrogel- Adsorbed Recombinant Ricin Vaccine (RiVax). Clin Vaccine Immunol, 2012.
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The need for continued development of ricin countermeasures

Reisler, R.B. and L.A. Smith, The need for continued development of ricin countermeasures. Adv Prev Med, 2012. 2012: p. 149737.
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Nucleoprotein nanostructures combined with adjuvants adapted to the neonatal immune context: a candidate mucosal RSV vaccine

Remot, A., et al., Nucleoprotein nanostructures combined with adjuvants adapted to the neonatal immune context: a candidate mucosal RSV vaccine. PLoS One, 2012. 7(5): p. e37722.
Paper

Immunity to ricin: fundamental insights into toxin- antibody interactions

O'Hara, J.M., A. Yermakova, and N.J. Mantis, Immunity to ricin: fundamental insights into toxin- antibody interactions. Curr Top Microbiol Immunol, 2012. 357: p. 209-41.
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Activation of Toll-like receptor 3 (TLR3) amplifies mesenchymal stem cell trophic factors and enhances therapeutic potency

Mastri, M., et al., Activation of Toll-like receptor 3 (TLR3) amplifies mesenchymal stem cell trophic factors and enhances therapeutic potency. Am J Physiol Cell Physiol, 2012.
Paper

Structure of RiVax: a recombinant ricin vaccine

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Legler, P.M., et al., Structure of RiVax: a recombinant ricin vaccine. Acta Crystallogr D Biol Crystallogr, 2011. 67(Pt 9): p. 826-30.
Paper

Ricin Vaccine Development

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Smallshaw, J.E. and E.S. Vitetta, Ricin Vaccine Development. Curr Top Microbiol Immunol, 2012. 357: p. 259-72.
Paper

Protective immunity to ricin toxin conferred by antibodies against the toxin’s binding subunit (RTB)

Yermakova, A. and N.J. Mantis, Protective immunity to ricin toxin conferred by antibodies against the toxin's binding subunit (RTB). Vaccine, 2011. 29(45): p. 7925-35.
Paper

Evaluation of a ricin vaccine candidate (RVEc) for human toxicity using an in vitro vascular leak assay

Porter, A., et al., Evaluation of a ricin vaccine candidate (RVEc) for human toxicity using an in vitro vascular leak assay. Toxicon, 2011. 58(1): p. 68-75.