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RiVax®

Paper

Protective Effect of Two Recombinant Ricin Subunit Vaccines in the New Zealand White Rabbit Subjected to a Lethal Aerosolized Ricin Challenge: Survival, Immunological Response and Histopathological Findings

McLain, D.E., et al., Protective Effect of Two Recombinant Ricin Subunit Vaccines in the New Zealand White Rabbit Subjected to a Lethal Aerosolized Ricin Challenge: Survival, Immunological Response and Histopathological Findings. Toxicol Sci, 2011.
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Process development and cGMP manufacturing of a recombinant ricin vaccine: An effective and stable recombinant ricin a-chain vaccine-RVEc

Meagher, M.M., et al., Process development and cGMP manufacturing of a recombinant ricin vaccine: An effective and stable recombinant ricin a-chain vaccine-RVEc. Biotechnol Prog, 2011.
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Progress in Biological Threat Agent Vaccine Development: A Repeat-Dose Toxicity Study of a Recombinant Ricin Toxin A-Chain (rRTA) 1-33/44-198 Vaccine (RVEc) in Male and Female New Zealand White Rabbits

McLain, D.E., et al., Progress in Biological Threat Agent Vaccine Development: A Repeat-Dose Toxicity Study of a Recombinant Ricin Toxin A-Chain (rRTA) 1-33/44-198 Vaccine (RVEc) in Male and Female New Zealand White Rabbits. Int J Toxicol, 2011.
Paper

Distinctive immunomodulatory and inflammatory properties of the Escherichia coli type II heat-labile enterotoxin LT-IIa and its B pentamer following intradermal administration

Mathias-Santos, C., et al., Distinctive immunomodulatory and inflammatory properties of the Escherichia coli type II heat-labile enterotoxin LT-IIa and its B pentamer following intradermal administration. Clin Vaccine Immunol, 2011. 18(8): p. 1243-51.
Paper

Introduction of a disulfide bond leads to stabilization and crystallization of a ricin immunogen

Compton, J.R., et al., Introduction of a disulfide bond leads to stabilization and crystallization of a ricin immunogen. Proteins, 2011. 79(4): p. 1048-60.
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Targeting of antigens to skin dendritic cells: possibilities to enhance vaccine efficacy

Romani, N., et al., Targeting of antigens to skin dendritic cells: possibilities to enhance vaccine efficacy. Immunol Cell Biol, 2010. 88(4): p. 424-30.
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Principles of antidote pharmacology: an update on prophylaxis, post- exposure treatment recommendations and research initiatives for biological agents

Ramasamy, S., et al., Principles of antidote pharmacology: an update on prophylaxis, post- exposure treatment recommendations and research initiatives for biological agents. Br J Pharmacol, 2010. 161(4): p. 721-48.
Paper

olding domains within the ricin toxin A subunit as targets of protective antibodies

O'Hara, J.M., et al., Folding domains within the ricin toxin A subunit as targets of protective antibodies. Vaccine, 2010. 28(43): p. 7035-46.
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A monoclonal immunoglobulin G antibody directed against an immunodominant linear epitope on the ricin A chain confers systemic and mucosal immunity to ricin

Neal, L.M., et al., A monoclonal immunoglobulin G antibody directed against an immunodominant linear epitope on the ricin A chain confers systemic and mucosal immunity to ricin. Infect Immun, 2010. 78(1): p. 552-61.
Paper

Epidermal Langerhans cells rapidly capture and present antigens from C-type lectin-targeting antibodies deposited in the dermis

Flacher, V., et al., Epidermal Langerhans cells rapidly capture and present antigens from C-type lectin-targeting antibodies deposited in the dermis. J Invest Dermatol, 2010. 130(3): p. 755-62.