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ThermoVax®

Paper

Vaccine Thermostable bivalent filovirus vaccine protects against severe and lethal Sudan ebolavirus and marburgvirus infection Publication

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Albert To, Teri Ann S. Wong, Aquena H. Ball, Michael M. Lieberman, Jake Yalley-Ogunro, Mehtap Cabus, Sara Nezami, Fabian Paz, Hanne Andersen Elyard, Viktoriya Borisevich, Krystle N. Agans, Daniel J. Deer, Courtney Woolsey, Robert W. Cross, Thomas W. Geisbert, Oreola Donini, Axel T. Lehrer,
Thermostable bivalent filovirus vaccine protects against severe and lethal Sudan ebolavirus and marburgvirus infection,
Vaccine, 2023, ISSN 0264-410X.
Poster

Preservation of Quaternary Structure in Thermostable, Lyophilized Ebola Glycoprotein Vaccines

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Preston, K.B., Monticello, C.R., Wong, T.A., Donini, O., Lehrer, A.T., Randolph, T.W. Preservation of Quaternary Structure in Thermostable, Lyophilized Ebola
Glycoprotein Vaccines. Poster presentation at the 2019 Colorado Protein Stability Conference. July 30-August 1, 2019.
Poster

Preliminary Stability Assays for a Thermostable, Trivalent Filovirus Vaccine

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Preston, K.B., Monticello, C.R., Wong, T.A., Donini, O., Lehrer, A.T., Randolph, T.W. Preliminary Stability Assays for a Thermostable, Trivalent Filovirus Vaccine. Poster presentation at the 2019 Colorado Protein Stability Conference. July 30-August 1, 2019.
Paper

Thermostable Ebola virus vaccine formulations lyophilized in the presence of aluminum hydroxide

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Ebola: Chisholm F, Kang JT, Dong M, Lewis K, Namekar M, Lehrer AT, Randolph TW. Thermostable Ebola Virus Vaccine Formulations Lyophilized in the Presence of Aluminum Hydroxide. Eur. J. Pharm. Bipharm. 2019. 136: 213-20.
Poster

Thermostable Lyophilized Ebola Vaccine Formulations

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Chisholm, C.F., Kang, T.K., Lehrer, A., Donini, O.,, Randolph, T.W. Thermostable Lyophilized Ebola Vaccine Formulations. Poster presentation at the 2016 Workshop on Protein Aggregation and Immunogenicity. August 2-4, 2016.
Paper

Glassy-State Stabilization of a Dominant Negative Inhibitor Anthrax Vaccine Containing Aluminum Hydroxide and Glycopyranoside Lipid A Adjuvants

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Anthrax: Hassett K.J., Vance D.J., Jain, N.K., Sahni, N., Rabia, L.A., Cousins, M.C., Joshi, S. Volkin, D.B., Middaugh, C.R., Mantis, N.J., Carpenter, J.F., Randolph, T.W. Glassy-state stabilization of a dominant negative inhibitor anthrax vaccine containing aluminum hydroxide and glycopyranoside lipid adjuvants. J. Pharm. Sci 2015. 104(2): 627-39.
Paper

Combination of Two Candidate Subunit Vaccine Antigens Elicits Protective Immunity to Ricin and Anthrax Toxin in Mice

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Ricin+Anthrax: Vance, D.J., Rong, Y., Brey, R.N., Mantis, N.J. Combination of two candidate subunit vaccine antigens elicits protective immunity to ricin and anthrax toxin in mice. Vaccine 2015. 33(3): 417-21.
Paper

Development of a highly thermostable, adjuvanted human papillomavirus vaccine

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HPV: Hassett, K.J., Meinerz N.M., Semmelmann F., Cousins M.C., Garcea, R.L, Randolph, T.W. Development of a highly thermostable, adjuvanted human papillomavirus vaccine. Eur. J. Pharm. Biopharm. 2015.
Paper

Thermostable ricin vaccine protects rhesus macaques against aerosolized ricin: Epitope-specific neutralizing antibodies correlate with protection

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Ricin: Roy, C.J., Brey, R.N., Mantis, N.J., Mapes K., Pop, I.V., Pop, L.M., Ruback, S., Zilleen, S.Z., Doyle-Meyers, L., Vinet-Oliphant, H.S., Didier, P.J., Vitetta,, E.S. Thermostable ricin vaccine protests rhesus macaques against aerosolized ricin: Epitope-specific neutralizing antibodies correlate with protection. PNAS 2015. 112(12): 3782-87.
Poster

Thermostable Subunit Vaccine Results in Protective Immunity in Rhesus Macaques in an Inhalational Ricin Model – May 2015

Roy, C.J., Mantis, N., Brey, R., Vitetta, E., Donini, O. Thermostable Subunit Vaccine Results in Protective Immunity in Rhesus Macaques in an Inhalational Ricin Model. Poster presentation at the 2015 Chemical Biological Defense Science and Technology conference.