
SGX943
Paper
Regulation of MyD88 aggregation and the MyD88-dependent signaling pathway by sequestosome 1 and histone deacetylase 6
Into T, Inomata M, Niida S, Murakami Y, Shibata K. 2010. Regulation of MyD88 aggregation and the MyD88-dependent signaling pathway by sequestosome 1 and histone deacetylase 6. J Biol Chem 285: 35759-69
Paper
Molecular insights into Burkholderia pseudomallei and Burkholderia mallei pathogenesis
Galyov EE, Brett PJ, DeShazer D. 2010. Molecular insights into Burkholderia pseudomallei and Burkholderia mallei pathogenesis. Annu Rev Microbiol 64: 495-517
Poster
Sequestosome-1/p62 is the key intracellular target of innate defense regulator peptide
Kielczewska A, Yu HB, Rozek A, Takenaka S, Li Y, Guarna MM, North JR, Foster LJ, Finlay BB, Donini O. Sequestosome-1 / p62 is the key intracellular target of innate defense regulator peptide. Poster presentation at Keystone Symposium on The Macrophage: The intersection of Pathogenic & Protective Inflammation. 2010.
Poster
Reduced Infection and Mucositis in Chemotherapy-Treated Animals Following Innate Defense Modulation Using a Novel Drug Candidate
Donini O, Watkins BA, Palardy J, Opal S, Sonis S, Abrams MJ, North JR. Reduced Infection and Mucositis in Chemotherapy-Treated Animals Following Innate Defense Modulation Using a Novel Drug Candidate. 2010. Blood (ASH Annual Meeting Abstracts) 2010; 116:3781.
Poster
IDRs protect leukopenic animals Innate defense regulators are a novel macrophage-mediated therapy to treat infectious and inflammatory diseases
Takenaka S, Rozek A, Kielczewska A, Thorson L, North JR, Finlay BB, Donini O. Innate Defense Regulators are a novel macrophage-mediated therapy to treat infectious and inflammatory diseases. Poster presentation at Keystone Symposium on The Macrophage: The intersection of Pathogenic & Protective Inflammation. 2010.
Paper
Sequestosome-1/p62 is the key intracellular target of innate defense regulator peptide
Yu HB, Kielczewska A, Rozek A, Takenaka S, Li Y, Thorson L, et al. Sequestosome-1/p62 is the key intracellular target of innate defense regulator peptide. J Biol Chem. 2009;284,36007-11.
Paper
The Adaptor Protein p62/SQSTM1 Targets Invading Bacteria to the Autophagy Pathway
Zheng YT, Shahnazari S, Brech A, Lamark T, Johansen T, Brumell JH. 2009. The adaptor protein p62/SQSTM1 targets invading bacteria to the autophagy pathway. J Immunol 183: 5909-16
Paper
Listeria monocytogenes ActA-mediated escape from autophagic recognition
Yoshikawa Y, Ogawa M, Hain T, Yoshida M, Fukumatsu M, et al. 2009. Listeria monocytogenes ActA-mediated escape from autophagic recognition. Nat Cell Biol 11: 1233-40
Paper
Prevalence of Burkholderia pseudomallei in Guangxi, China
Ma, G., D. Zheng, Q. Cai, and Z. Yuan. 2010. Prevalence of Burkholderia pseudomallei in Guangxi, China. Epidemiology and infection 138:37-39
Poster
SQSTM-1/p62: A Novel Therapeutic Target in Infectious and Inflammatory Disease
Yu H, Kielczewska A, Rozek A, Takenaka S, Li Y, Guarna M, Thorson L, Hancock R, North J, Foster L, Donini O, Finlay B. SQSTM-1/p62: A Novel Therapeutic Target in Infectious and Inflammatory Disease. Poster Presentation at 49th Interscience Conference on Antimicrobial Agents and Chemotherapy. 2009.